We have expanded to the US

With the acquisition of US-based CRO C3 Research,
Avance Clinical now offers its international biotech clients
CRO services in Australia, New Zealand, and North America


The Australian CRO
for International

An agile solutions-focussed culture
Maximizing value, speed, and data quality

Globally accepted data

Avance Clinical has a world-class reputation for quality data that is accepted by all regulatory authorities including FDA. In-house Medidata trained specialists.

Rapid start-up

Avance Clinical can deliver Site Initiation Visit (SIV) and Study Start in 5 – 6 weeks. No IND required.

Extend budget by 43.5%

Avance Clinical can secure the maximum rebate on your clinical trial spend with the Australian Government clinical trial rebate program.

Industry-leading technology

Avance Clinical invests heavily in the industry-leading technology platforms to support speed, communications, and regulatory compliance.

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An Experienced Team

Learn more about us here

Recent features and awards

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Established & Proven over 24 years

Agile and solutions-focussed

Avance Clinical is the largest full-service Australian CRO delivering quality clinical trials with globally accepted data in Australia and New Zealand for international biotechs.

Frost & Sullivan awards

Avance Clinical, a Frost & Sullivan Asia-Pacific CRO Best Practices Award recipient for the past two years, has been providing CRO services in the region for the past 24 years.

The company’s clients are biotechs in their early phases of drug development that need fast, agile, and adaptive solution-oriented clinical research services.

Pre-clinical through to Phase 1 and 2

Avance Clinical offers pre-clinical services with their experienced ClinicReady team right through to Phases 1 and 2 leveraging significant Government incentive rebates of 43.5% and rapid start-up regulatory processes.

With experience across more than 105 indications, the CRO can deliver world-class results and high-quality internationally accepted data for FDA and EMA review.

Avance Clinical delivers customised solutions designed around specific client needs rather than a one size fits all approach.


As a company, Avance Clinical has focused on state-of-the-art technology and systems across all functional areas to provide clients with the most effective processes. Medidata, Oracle, and Medrio are just some of the technology partners.

Experienced Team

More than 200 In-House CRO Specialists

Avance Clinical had its genesis in the University of South Australia in the early 1980s as the Centre for Pharmaceutical Research, when a group of academic scientists began providing clinical research and bioanalytical services to the local pharmaceutical industry.

Since then, it has grown to become the leading mid-sized CRO servicing the international drug development industry.

Avance Clinical offers some of the most extensive in-house clinical services including:

  • ClinicReady – pre-clinical services
  • Clinical Monitoring Management
  • Data Management
  • eClinical Solutions
  • Safety and Pharmacovigilance
  • Medical Writing
  • Project Management
  • Statistics and Pharmacokinetics
  • Quality Assurance

Pre-clinical ClinicReady

The ClinicReady range of services constitutes a natural progression in Avance Clinical’s role as the premier provider of early drug development support to the biotechnology sector. The company recognises the major challenges faced by small biotechnology companies, particularly start-up companies who seek to drive their novel therapeutics to demonstration of safety and preliminary clinical Proof of Concept.


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Medical Writing

The Avance Clinical biostatistics and pharmacokinetics experts provide specialist guidance for your clinical research trial design and analysis.

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Data Management

Avance Clinical’s data management team has gained a world-class reputation for accuracy, precision, and quality of their biostatistics and pharmacokinetic (PK) analysis.

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Safety and Pharmacovigilance

Clinical trials safety monitoring and reporting is vital to ensure participant safety, data integrity, and regulatory compliance.

Regulatory guidelines around clinical trial safety monitoring and reporting demand strict safety management procedures, from a highly-skilled, and experienced safety team.

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eClinical Solutions

The Avance Clinical team works with eClinical leaders such as Medrio, Medidata, and Oracle to offer regulatory compliant and patient-centric tools for rapid start-up and continual data flow.

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Quality Assurance

Data quality is at the heart of everything at Avance Clinical. Delivered by our highly experienced staff we support our clients with their clinical trial audit to achieve their quality objectives for their clinical research trials.

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Clinical Monitoring Management

Avance Clinical has experienced clinical monitoring staff across all phases of clinical trials and can collaboratively support the Australian CRO arm of multinational trials.

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Project Management

Avance Clinical provides each clinical research trial with a dedicated Project Manager to ensure that milestones are reached, timelines are met and that our clients receive effective communication and ongoing status reports.

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“It has been a great pleasure working with you on this project. Your flexibility, pragmatic approaches and focus on the work has been exceptional. I am looking forward to have the next compound entering the clinic with you.”

Head of Drug Discovery, Pharmaxis Ltd

“Working with the Avance Team has helped us to develop and complete high quality and compliant clinical studies. I especially appreciate their penchant for communication, quality and pragmatism.”

Sr. Vice President, Regulatory, Quality & Clinical Affairs, Atossa Genetics, Inc.

“Having conducted several Phase I studies in Australia it made sense to continue in the country with our Phase II program, particularly given the high-quality support we have received from our CRO.”

Atossa Therapeutics Inc.

“Avance Clinical has proven themselves to be my “Champions”, anticipating problems and always acting in the interest of getting the trial done professionally, resourcefully, and in alignment with the goals of the Sponsor and well-being of the volunteers.”

Chairman of the Board and Chief Medical Officer, BioFactura Inc

“Medrio has supported numerous study starts in Australia, over 150 with Avance Clinical alone, and we’re always impressed with the speed of their timelines.”

CEO Mike Novotny (former), Medrio

“We reached out to Avance to refine and polish a substantive and comprehensive drug study clinical trial ethics application. The Avance Team were remarkably quick to respond to our enquiry. Avance provided us within a very short turn-around period a comprehensive appraisal of the documentation covering all elements including protocol, ethics, investigator brochure and patient information and consent. Avance were highly engaged with the research investigator team and suggested changes were clear and well rationalised. The services provided were cost-effective and well justified. I have no hesitation to recommend Avance as a quality CRO”.

Curtin Health Innovation Research Institute
Studies in the past 5 years
Experienced Team Members
Participants past 5 years
Years of of CRO experience

“Avance Clinical’s clients are international biotech companies primarily from the United States, United Kingdom, Japan, China, South Korea, Taiwan, France, and Germany. These clients are seeking a premium CRO with the same experience and advanced technology platforms offered by the major global CROs, but with an agile and customer focused approach to clinical management in Australia and New Zealand.”

Supriya Lala KunduBest Practices Research Analyst, Frost & Sullivan

Latest News

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October 27, 2022 in Other news

Avance Clinical Sponsors China BioPharma Award at the Global Scrip Awards, London

Adelaide, Australia/San Diego, USA – Avance Clinical, the leading Australian-based biotech CRO with US operations will sponsor and present the China BioPharma Award at the global biotech Scrip Awards in…
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September 28, 2022 in Company Awards

Avance Clinical Wins International Health Award for Biotech CRO Services

Australia – Avance Clinical, the leading Australian-based biotech CRO with US operations has won the South Australian Premier’s Export Awards - International Health category. The award recognises excellence in clinical services exports.…
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September 6, 2022 in Company News


https://vimeo.com/746663903 Sydney, Australia/San Diego, USA – Avance Clinical, the Australian CRO for biotechs, has expanded into North America with the acquisition of CRO partner company C3 Research Associates to enable…
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